The advent of quantum computing is going to revolutionize computer science as we know it. The “quantum era” is right around the corner and promises to impact program computation to the point that it might even be possible to solve NP-complete problems. All major software companies, from IBM to Google, and others, are investing hundreds of billion dollars to define novel hardware and software instruments to reach quantum supremacy and embrace the change. However, large scale pure quantum software systems are far to come yet, so there is a growing interest in developing hybrid Quantum Based software Systems (QBSs), where quantum components are integrated in traditional software applications. Still, the development of QBSs remains challenging for a variety of reasons. The lack of multidisciplinary skills, the primordial programming language support, the absence of integrated development environments, or the lack of a development community are just some of the reasons why there is an increasing interest in the emerging research area of quantum software engineering, that is, the definition of methods, practices, and tools to support the development of QBSs.